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Clinical and preclinical studies suggest that lactate-enriched solutions confer notable benefits in traumatic brain injury and myocardial ischemia, including reductions in cognitive deficits, improvements in cerebral blood flow and attenuation of reperfusion injuries through mechanisms such as anti-inflammatory effects and provision of alternative energy substrates (156,162)

Salvianolic acid B (from Salvia miltiorrhiza) protects cardiomyocytes during I/R by scavenging ROS and inhibiting apoptosis through PI3K/Akt and ERK pathways ( Limiting infarct expansion and fibrosis: After an MI, the reduction of infarct expansion and scar formation is crucial

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